The age-range of 35-65 was an approximation by the FHCRC team. This is a ‘useful’ age range as around this age most chronic diseases are present. There are attractive reasons for choosing a younger cohort, allowing us to study early-onset cancers, cardiovascular diseases, psychiatric illnesses, sexually transmitted diseases, etc. Measuring past exposure (for older cohorts) would be both a limitation and a great challenge to this study. The FHCRC realizes this and have indicated that the National Institutes of Health USA have been discussing about the technologies that would be available to measure and monitor exposures continuously or intermittently.


